Primary Information |
|---|
| BoMiProt ID | Bomi6058 |
|---|
| Protein Name | Glycerol-3-phosphate acyltransferase 4 |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | A3FPG8 |
|---|
| Milk Fraction | Exosomes |
|---|
| Ref Sequence ID | NP_001077138.1 |
|---|
| Aminoacid Length | 456 |
|---|
| Molecular Weight | 52055 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | GPAT4 |
|---|
| Gene ID | 511614 |
|---|
| Protein Existence Status | reviewed |
|---|
Secondary Information |
|---|
| Protein Function | Participate in CDP-diacylglycerol biosynthesis.Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone. |
|---|
| Biochemical Properties | The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. |
|---|
| PTMs | Glycosylation |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|A3FPG8|GPAT4_BOVIN Glycerol-3-phosphate acyltransferase 4 OS=Bos taurus OX=9913 GN=GPAT4 PE=3 SV=1
MFLLLPFDSLIVSLLGISLTVLFTLLLVFIIVPAVFGVSFGIRKLYMKTLLKIFAWATLR
MERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCR
KGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCLLLSLRI
ALAFTGISLLVVGTTMVGYLPNGRFKEFLSKHVHLMCYRICVRALTAIITYHDRKNRPRN
GGICVAN*247HTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHL
VARRLTEHVQDKSKLPILIFPEGTCIN*327N*328TSVMMFKKGSFEIGATVYPVAIKYDPQFGDAF
WN*362SSKYGMVTYLLRMMTSWAIVCSVWYLPPMTRQAEEDAVQFANRVKSAIARQGGLVDLL
WDGGLKREKVKDTFKEEQQKLYSKMIVGNHEDRSRS |
|---|
| Predicted Disorder Regions | NA |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | 2TMHs; (19-41),(178-200) |
|---|
