Primary Information
BoMiProt ID	Bomi6046
Protein Name	Glutathione hydrolase 7/Gamma-glutamyltransferase 7/Gamma-glutamyltransferase-like 3/Gamma-glutamyltranspeptidase 7/GGT 7
Organism	Bos taurus
Uniprot ID	Q0V8L2
Milk Fraction	whey
Ref Sequence ID	NP_001069869.1
Aminoacid Length	662
Molecular Weight	70652
FASTA Sequence	Download
Gene Name	GGT7/GGTL3
Gene ID	615929
Protein Existence Status	Reviewed
Secondary Information
Protein Function	involved in the pathway glutathione metabolism.It cleaves glutathione conjugates.
Biochemical Properties	Heterodimer composed of the light and heavy chains. The active site is located in the light chain.Catalyses the following reaction an α-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-α-aminoacyl-[peptide]
PTMs	Glycosylation and Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q0V8L2|GGT7_BOVIN Glutathione hydrolase 7 OS=Bos taurus OX=9913 GN=GGT7 PE=2 SV=1 MAAENEASQESALGAYS*17PVDYMSITSFPRLPEDEPAPAVPLRGRKDEDAFLGDPDTDPDS FLKSARLQRLPS*72SSSEMGS*79QDGS*83PLRETRKDPFSAAASECSCRQDGLTVIVTACLTFATG VTVALIMQIYFGDPQIFHQGAVVTDAARCTSLGIEVLSKQGSSVDAAVAAALCLGIVAPH SSGLGGGGVMLVHDIRRN*198KSHLIDFRESAPGALREEALQRSWETKPGLLVGVPGMVKGLH EAHQLYGRLPWSQVLAFAAAVAQDGFN*267VTHDLAQALAEQPPPN*283ASDRFRETFLPMGHPPL PGSLLRRPDLAAVLEVLGTYGPAAFYAGGN*330LTLEMVAEAQHAGGVITEEDFSN*353YSALLEK PVCGVYRGHLVLSPRPPHTGPALISALNILEGFN*394LTSLVSREQALHWVAETLKIALALAS RLGDPIYDSTITESMDDMLSKVEAAYFRGQIN*452DSQAAPVPLLPIYELNGAPTAAQVLIMG PDDFIVAMVSSLNRPFGSGLITPSGILLNSQMLDFSWPN*519RTANHPAPSLENSVQPGKRPL SFLLPTVVRPAEGLCGTYLALGANGAARGLSGLTQVLLNVLTLNRN*586LSDSLARGRLHPDL QTNLLQVDSEFTEEEIEFLEARGHHVEKVDVLSWVHGSRRTNNFIIGVKDPRSPDAAGAT IL
Predicted Disorder Regions	1-34,47-94
DisProt Annotation
TM Helix Prediction	1TMH; (109 131)
Bibliography	Harhay, G. P., Sonstegard, T. S., Keele, J. W., Heaton, M. P., Clawson, M. L., Snelling, W. M., Wiedmann, R. T., Van Tassell, C. P., & Smith, T. P. (2005). Characterization of 954 bovine full-CDS cDNA sequences. BMC genomics, 6, 166. https://doi.org/10.1186/1471-2164-6-166