Search by BoMiProt ID - Bomi5954

Primary Information

BoMiProt ID Bomi5954
Protein Name GATA zinc finger domain-containing protein 1
Organism Bos taurus
Uniprot IDA2VDY6
Milk FractionWhey
Ref Sequence ID NP_001075092.1
Aminoacid Length 272
Molecular Weight 28884
FASTA Sequence Download
Gene Name GATAD1
Gene ID 784921
Protein Existence Status reviewed

Secondary Information

Protein Function GATAD1 binds to a histone modification site that regulates gene expression.
PTMs Acetylation, isopeptide bond formation, Ubiquitinylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions (1-127)
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs acetylation may be required for chromatin occupancy
Bibliography 1.Lamonica, J. M., Vakoc, C. R., & Blobel, G. A. (2006). Acetylation of GATA-1 is required for chromatin occupancy. Blood, 108(12), 3736–3738. 2.Sun, W., Zhang, Y., Wong, K. C., Liu, K., Yang, Y., Wu, B., Tong, J., Chan, A., Chan, H., & Yu, J. (2018). Increased expression of GATA zinc finger domain containing 1 through gene amplification promotes liver cancer by directly inducing phosphatase of regenerating liver 3. Hepatology (Baltimore, Md.), 67(6), 2302–2319.