Search by BoMiProt ID - Bomi5917


Primary Information

BoMiProt ID Bomi5917
Protein Name G2/mitotic-specific cyclin-B1
Organism Bos taurus
Uniprot IDQ1LZG6
Milk Fractionwhey
Ref Sequence ID NP_001039337.1
Aminoacid Length 427
Molecular Weight 47658
FASTA Sequence Download
Gene Name CCNB1
Gene ID 327679
Protein Existence Status Reviewed

Secondary Information

Protein Function It is essential for the control of the cell cycle at the G2/M (mitosis) transition.
PTMs Acetylation and Phosphorylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
>sp|Q1LZG6|CCNB1_BOVIN G2/mitotic-specific cyclin-B1 OS=Bos taurus OX=9913 GN=CCNB1 PE=2 SV=1 MALRITRNTKISAENKAKISMAGAKRVPVAAVATSKPGLRPRTALGDIGNKVSEQPQAKL PLKKEAKTLASGKVTAKKVPKPLEKAPVPVPEPQPEPEPEPEHVKEDKLSPEPILVDTPS*120 PS*122PMETS*127GCAPAEEYLCQAFS*141DVILAVSDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQA VKPKYLMGREVTGNMRAILIDWLVQVQIKFRLLQETMYMTVSIIDRFMQDTYVPKKMLQL VGVTAMFVASKYEEMYPPEIGDFAFVTDNTYTKFQIRQMEMKILRALNFSLGRPLPLHFL RRASKIGEVDVELHT*315LAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKVLDNGEWTPTLQ HYLSYTEESLLVVMQHLAKNVVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNSALVQDL AKAVAKV
Predicted Disorder Regions 1-134
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs Phosphorylated by PLK1 at Ser-127 on centrosomes during prophase: phosphorylation by PLK1 does not cause nuclear import.
Bibliography Ye, Q., Lei, L., & Aili, A. X. (2015). Identification of potential targets for ovarian cancer treatment by systematic bioinformatics analysis. European journal of gynaecological oncology, 36(3), 283–289.