Primary Information |
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| BoMiProt ID | Bomi5917 |
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| Protein Name | G2/mitotic-specific cyclin-B1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q1LZG6 |
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| Milk Fraction | whey |
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| Ref Sequence ID | NP_001039337.1 |
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| Aminoacid Length | 427 |
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| Molecular Weight | 47658 |
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| FASTA Sequence |
Download |
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| Gene Name | CCNB1 |
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| Gene ID | 327679 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | It is essential for the control of the cell cycle at the G2/M (mitosis) transition. |
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| PTMs | Acetylation and Phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q1LZG6|CCNB1_BOVIN G2/mitotic-specific cyclin-B1 OS=Bos taurus OX=9913 GN=CCNB1 PE=2 SV=1
MALRITRNTKISAENKAKISMAGAKRVPVAAVATSKPGLRPRTALGDIGNKVSEQPQAKL
PLKKEAKTLASGKVTAKKVPKPLEKAPVPVPEPQPEPEPEPEHVKEDKLSPEPILVDTPS*120
PS*122PMETS*127GCAPAEEYLCQAFS*141DVILAVSDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQA
VKPKYLMGREVTGNMRAILIDWLVQVQIKFRLLQETMYMTVSIIDRFMQDTYVPKKMLQL
VGVTAMFVASKYEEMYPPEIGDFAFVTDNTYTKFQIRQMEMKILRALNFSLGRPLPLHFL
RRASKIGEVDVELHT*315LAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKVLDNGEWTPTLQ
HYLSYTEESLLVVMQHLAKNVVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNSALVQDL
AKAVAKV |
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| Predicted Disorder Regions | 1-134 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Significance of PTMs | Phosphorylated by PLK1 at Ser-127 on centrosomes during prophase: phosphorylation by PLK1 does not cause nuclear import. |
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| Bibliography | Ye, Q., Lei, L., & Aili, A. X. (2015). Identification of potential targets for ovarian cancer treatment by systematic bioinformatics analysis. European journal of gynaecological oncology, 36(3), 283–289. |
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