Primary Information |
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BoMiProt ID | Bomi5917 |
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Protein Name | G2/mitotic-specific cyclin-B1 |
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Organism | Bos taurus |
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Uniprot ID | Q1LZG6 |
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Milk Fraction | whey |
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Ref Sequence ID | NP_001039337.1 |
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Aminoacid Length | 427 |
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Molecular Weight | 47658 |
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FASTA Sequence |
Download |
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Gene Name | CCNB1 |
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Gene ID | 327679 |
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Protein Existence Status | Reviewed |
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Secondary Information |
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Protein Function | It is essential for the control of the cell cycle at the G2/M (mitosis) transition. |
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PTMs | Acetylation and Phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q1LZG6|CCNB1_BOVIN G2/mitotic-specific cyclin-B1 OS=Bos taurus OX=9913 GN=CCNB1 PE=2 SV=1
MALRITRNTKISAENKAKISMAGAKRVPVAAVATSKPGLRPRTALGDIGNKVSEQPQAKL
PLKKEAKTLASGKVTAKKVPKPLEKAPVPVPEPQPEPEPEPEHVKEDKLSPEPILVDTPS*120
PS*122PMETS*127GCAPAEEYLCQAFS*141DVILAVSDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQA
VKPKYLMGREVTGNMRAILIDWLVQVQIKFRLLQETMYMTVSIIDRFMQDTYVPKKMLQL
VGVTAMFVASKYEEMYPPEIGDFAFVTDNTYTKFQIRQMEMKILRALNFSLGRPLPLHFL
RRASKIGEVDVELHT*315LAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKVLDNGEWTPTLQ
HYLSYTEESLLVVMQHLAKNVVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNSALVQDL
AKAVAKV |
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Predicted Disorder Regions | 1-134 |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Significance of PTMs | Phosphorylated by PLK1 at Ser-127 on centrosomes during prophase: phosphorylation by PLK1 does not cause nuclear import. |
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Bibliography | Ye, Q., Lei, L., & Aili, A. X. (2015). Identification of potential targets for ovarian cancer treatment by systematic bioinformatics analysis. European journal of gynaecological oncology, 36(3), 283–289. |