Primary Information |
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| BoMiProt ID | Bomi5871 |
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| Protein Name | FXYD domain-containing ion transport regulator 6/Phosphohippolin |
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| Organism | Bos taurus |
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| Uniprot ID | Q3MHZ5 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001029571.1 |
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| Aminoacid Length | 95 |
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| Molecular Weight | 10465 |
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| FASTA Sequence |
Download |
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| Gene Name | FXYD6 |
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| Gene ID | 511064 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear |
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| Biochemical Properties | Most characterized FXYD proteins exhibit a similar structure with a single transmembrane domain and a type I orientation that is achieved, in some but not all cases, by the cleavage of an N-terminal signal peptide. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | 2 disordered segments; (19-29), (65-95) |
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| DisProt Annotation | |
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| TM Helix Prediction | 2TMHs;(3-21) and (36-58) |
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| Bibliography | Delprat B, Schaer D, Roy S, Wang J, Puel JL, Geering K. FXYD6 is a novel regulator of Na,K-ATPase expressed in the inner ear. J Biol Chem. 2007 Mar 9;282(10):7450-6. doi: 10.1074/jbc.M609872200. Epub 2007 Jan 5. PMID: 17209044. |
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