Primary Information
BoMiProt ID	Bomi5713
Protein Name	Fatty acid desaturase 6
Organism	Bos taurus
Uniprot ID	A2VE15
Milk Fraction	Whey,exosome
Ref Sequence ID	NP_001075191.1
Aminoacid Length	342
Molecular Weight	38614
FASTA Sequence	Download
Gene Name	FADS6
Gene ID	523867
Protein Existence Status	reviewed
Secondary Information
Protein Function	Fatty acid desaturase 6 is one of the Fattyacid desaturase which plays key roles in synthesizing Polyunsaturated fatty acids (PUFAs).
Biochemical Properties	It is involved in the pathway of fatty acid metabolism, which is a part of Lipid metabolism.
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	NA
Predicted Disorder Regions	(1-13)
DisProt Annotation
TM Helix Prediction	2TMHs; (65-83),(152-170)
Additional Comments	Peroxisome proliferator-activated receptor alpha b (PPARαb) played a vital role in ToFads6 regulation and may promote the biosynthesis of long-chain polyunsaturated fatty acids by regulating ToFads6 expression.
Bibliography	1.Zhu KC, Song L, Guo HY, Guo L, Zhang N, Liu BS, Jiang SG, Zhang DC. Identification of Fatty Acid Desaturase 6 in Golden Pompano Trachinotus Ovatus (Linnaeus 1758) and Its Regulation by the PPARαb Transcription Factor. Int J Mol Sci. 2018 Dec 21;20(1):23. doi: 10.3390/ijms20010023. PMID: 30577588; PMCID: PMC6337163. 2.Lee JM, Lee H, Kang S, Park WJ. Fatty Acid Desaturases, Polyunsaturated Fatty Acid Regulation, and Biotechnological Advances. Nutrients. 2016 Jan 4;8(1):23. doi: 10.3390/nu8010023. PMID: 26742061; PMCID: PMC4728637.