Primary Information |
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| BoMiProt ID | Bomi5623 |
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| Protein Name | Eukaryotic translation initiation factor 3 subunit L/Eukaryotic translation initiation factor 3 subunit 6-interacting protein/Eukaryotic translation initiation factor 3 subunit E-interacting protein |
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| Organism | Bos taurus |
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| Uniprot ID | Q3ZCK1 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001030373.1 |
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| Aminoacid Length | 564 |
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| Molecular Weight | 66727 |
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| FASTA Sequence |
Download |
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| Gene Name | EIF3L |
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| Gene ID | 514449 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | myometrium |
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| Protein Function | The 67-kDa L subunit of human eukaryotic translation initiation factor 3 (eIF3L) is one of the subunits of the mammalian translation initiation factor eIF3. The eIF3 factor plays a central role in translation initiation by recruiting the 40S ribosomal subunit and keeping it dissociated from the 60S subunit and by promoting the association of the former with mRNA and initiator Met-tRNA. |
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| PTMs | N6-acetylation at lysine |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| NA |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Morris-Desbois C, Réty S, Ferro M, Garin J, Jalinot P. The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3. J Biol Chem. 2001;276:45988–45995. doi: 10.1074/jbc.M104966200. 2. |
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