Search by BoMiProt ID - Bomi5333

Primary Information

BoMiProt ID Bomi5333
Protein Name Dynein regulatory complex protein 10/IQ domain-containing protein D
Organism Bos taurus
Uniprot IDQ17QH9
Milk FractionWhey
Ref Sequence ID NP_001069074.1
Aminoacid Length 444
Molecular Weight 51623
FASTA Sequence Download
Gene Name IQCD
Gene ID 513272
Protein Existence Status reviewed

Secondary Information

Protein Function imp for ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.role in sperm fertilisation and the acrosome reaction.
Biochemical Properties C-terminal conserved IQ motif domain and two coiled-coil domains
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 29-40, 422-444
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Zhang P, Jiang W, Luo N, Zhu W, Fan L. IQ motif containing D (IQCD), a new acrosomal protein involved in the acrosome reaction and fertilisation. Reprod Fertil Dev. 2019 Apr;31(5):898-914. doi: 10.1071/RD18416. Erratum in: Reprod Fertil Dev. 2019 Apr;31(5):1033. PMID: 30712531.