Search by BoMiProt ID - Bomi5291

Primary Information

BoMiProt ID Bomi5291
Protein Name Dual specificity protein phosphatase 10
Organism Bos taurus
Uniprot IDQ0IID7
Milk FractionWhey
Ref Sequence ID NP_001029897.2
Aminoacid Length 482
Molecular Weight 52389
FASTA Sequence Download
Gene Name DUSP10
Gene ID 541175
Protein Existence Status reviewed

Secondary Information

Protein Function adipocyte differentiation.brown adipogenesis. by regulating p38 phosphorylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 4 disordered segments; (1-6), (114-140), (158-166), (199-316)
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments DUSP10 can be used as a novel target protein for the regulation of obesity.
Bibliography Choi HR, Kim WK, Kim EY, Han BS, Min JK, Chi SW, Park SG, Bae KH, Lee SC. Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase. PLoS One. 2013 Aug 20;8(8):e72340. doi: 10.1371/journal.pone.0072340. PMID: 23977283; PMCID: PMC3748012.