Primary Information |
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| BoMiProt ID | Bomi5291 |
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| Protein Name | Dual specificity protein phosphatase 10 |
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| Organism | Bos taurus |
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| Uniprot ID | Q0IID7 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001029897.2 |
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| Aminoacid Length | 482 |
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| Molecular Weight | 52389 |
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| FASTA Sequence |
Download |
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| Gene Name | DUSP10 |
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| Gene ID | 541175 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | adipocyte differentiation.brown adipogenesis. by regulating p38 phosphorylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | 4 disordered segments; (1-6), (114-140), (158-166), (199-316) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Additional Comments | DUSP10 can be used as a novel target protein for the regulation of obesity. |
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| Bibliography | Choi HR, Kim WK, Kim EY, Han BS, Min JK, Chi SW, Park SG, Bae KH, Lee SC. Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase. PLoS One. 2013 Aug 20;8(8):e72340. doi: 10.1371/journal.pone.0072340. PMID: 23977283; PMCID: PMC3748012. |
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