Search by BoMiProt ID - Bomi5243

Primary Information

BoMiProt ID Bomi5243
Protein Name Dolichol-phosphate mannosyltransferase subunit 3 /Dolichol-phosphate mannose synthase subunit 3/DPM synthase subunit 3/Dolichyl-phosphate beta-D-mannosyltransferase subunit 3/Mannose-P-dolichol synthase subunit 3/MPD synthase subunit 3
Organism Bos taurus
Uniprot IDQ3ZC71
Milk FractionWhey,Casein,MFGM
Ref Sequence ID NP_001029532.1
Aminoacid Length 92
Molecular Weight 10142
FASTA Sequence Download
Gene Name DPM3
Gene ID 509745
Protein Existence Status reviewed

Secondary Information

Protein Function A component of Dolichol-phosphate mannose (DPM) synthase, which is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose.
Biochemical Properties Take part in protein glycosylation.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 1 disordered segment(80-92),disordered residues 1 and 2
DisProt Annotation
TM Helix Prediction 2 TMHs;( 7-25) and ( 37-59)
Bibliography Ashida H, Maeda Y, Kinoshita T. DPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3. J Biol Chem. 2006 Jan 13;281(2):896-904. doi: 10.1074/jbc.M511311200. Epub 2005 Nov 9. PMID: 16280320.