Primary Information |
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BoMiProt ID | Bomi5243 |
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Protein Name | Dolichol-phosphate mannosyltransferase subunit 3 /Dolichol-phosphate mannose synthase subunit 3/DPM synthase subunit 3/Dolichyl-phosphate beta-D-mannosyltransferase subunit 3/Mannose-P-dolichol synthase subunit 3/MPD synthase subunit 3 |
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Organism | Bos taurus |
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Uniprot ID | Q3ZC71 |
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Milk Fraction | Whey,Casein,MFGM |
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Ref Sequence ID | NP_001029532.1 |
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Aminoacid Length | 92 |
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Molecular Weight | 10142 |
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FASTA Sequence |
Download |
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Gene Name | DPM3 |
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Gene ID | 509745 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | A component of Dolichol-phosphate mannose (DPM) synthase, which is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. |
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Biochemical Properties | Take part in protein glycosylation. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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Predicted Disorder Regions | 1 disordered segment(80-92),disordered residues 1 and 2 |
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DisProt Annotation | |
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TM Helix Prediction | 2 TMHs;( 7-25) and ( 37-59) |
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Bibliography | Ashida H, Maeda Y, Kinoshita T. DPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3. J Biol Chem. 2006 Jan 13;281(2):896-904. doi: 10.1074/jbc.M511311200. Epub 2005 Nov 9. PMID: 16280320. |