Primary Information
BoMiProt ID	Bomi5230
Protein Name	DnaJ homolog subfamily B member 12
Organism	Bos taurus
Uniprot ID	Q58DR2
Milk Fraction	whey
Ref Sequence ID	NP_001017946.1
Aminoacid Length	370
Molecular Weight	41340
FASTA Sequence	Download
Gene Name	DNAJB12
Gene ID	533603
Protein Existence Status	Reviewed
Secondary Information
Protein Function	It acts as a co-chaperone with HSPA8/Hsc70 and is needed to promote protein folding and trafficking, prevent aggregation of target proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway
Biochemical Properties	Interacts (via J domain) with HSPA8/Hsc70
PTMs	Acetylation and Methylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	1-6, 20-23, 49-91, 172-196, 361-367
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Yamamoto, Y. H., Kimura, T., Momohara, S., Takeuchi, M., Tani, T., Kimata, Y., Kadokura, H., & Kohno, K. (2010). A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membrane proteins including CFTR. Cell structure and function, 35(2), 107–116. https://doi.org/10.1247/csf.10023