Search by BoMiProt ID - Bomi5084

Primary Information

BoMiProt ID Bomi5084
Protein Name Deoxyribose-phosphate aldolase/2-deoxy-D-ribose 5-phosphate aldolase/Phosphodeoxyriboaldolase/Deoxyriboaldolase/DERA
Organism Bos taurus
Uniprot IDQ3T0V9
Milk FractionWhey
Ref Sequence ID NP_001069496.1
Aminoacid Length 318
Molecular Weight 35246
FASTA Sequence Download
Gene Name DERA
Gene ID 534558
Protein Existence Status reviewed

Secondary Information

Protein Function It's function is to minimize or delay stress-induced damage by producing energy through deoxynucleoside degradation.
Biochemical Properties It converts 2-deoxy-d-ribose-5-phosphate into glyceraldehyde-3-phosphate and acetaldehyde, belongs to the core metabolism of living organisms.
PTMs Phosphorylation at Serine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments In Bacillus cereus dRib 5-P aldolase is involved in the catabolism of exogenous deox3,ribonucleosides. This spore-forming bacterium can grow on nucleosides as a carbon source, since it possesses an efficient catabolic pathway by which the pentose moiety of exogenous nucleosides may be utilized as an energy source
Bibliography 1.Salleron L, Magistrelli G, Mary C, Fischer N, Bairoch A, Lane L. DERA is the human deoxyribose phosphate aldolase and is involved in stress response. Biochim Biophys Acta. 2014 Dec;1843(12):2913-25. doi: 10.1016/j.bbamcr.2014.09.007. Epub 2014 Sep 16. PMID: 25229427. 2.Sgarrella F, Del Corso A, Tozzi MG, Camici M. Deoxyribose 5-phosphate aldolase of Bacillus cereus: purification and properties. Biochim Biophys Acta. 1992 Jan 9;1118(2):130-3. doi: 10.1016/0167-4838(92)90139-5. PMID: 1730028. 3. Mura. U.. Sgarrelta, F. and Ipata, P.L. (1978) J. Biol. Chem. 253, 79O5-7OO9. 4.lpata. P.L. Sgarrella. F. and Tozzi, M.G. (1985) Curt, Top. Ceil, Regul. 26, 4t9-432.