Primary Information
BoMiProt ID	Bomi5029
Protein Name	DDB1- and CUL4-associated factor 15
Organism	Bos taurus
Uniprot ID	Q3SZD5
Milk Fraction	whey
Ref Sequence ID	NP_001029857.1
Aminoacid Length	600
Molecular Weight	66269
FASTA Sequence	Download
Gene Name	DCAF15
Gene ID	539970
Protein Existence Status	Reviewed
Secondary Information
Protein Function	It acts as a substrate-recognition component of the DCX(DCAF15) complex
Biochemical Properties	The complex mediates ubiquitination and degradation of target proteins
PTMs	Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q3SZD5|DCA15_BOVIN DDB1- and CUL4-associated factor 15 OS=Bos taurus OX=9913 GN=DCAF15 PE=2 SV=1 MAPSSKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLS*50PRLFRKLPPR VCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDFSFYIYHLYWWEFNVHSKL KLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMVMSDENHRDI YISTVAVPPPGRCAACRDASRAHPGDPSAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKD QVVLLNTSYSLVACAVSVHSAGDSSFCQILYDHTTYPPAPPSPPGPQSPELPPVLPSLCP EAAPAWPSGPPDPS*314PAIAKAKEFVADIFRRAKEAKGGTSEEVRPPPCPGPSGSRCRLPSE PLGPGGEAVPRDSPPAAEAPAPEPGYVNYTKLYYVLGSGEGTEPEDEFEDDKISLPFVVT DLRGRNLRPMREQAVVQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILE VCPETNQVLINIGLLLLAFPSPTEEGQLRPKTYHTSLKVAWDLNTGIFVTVSVGDLTEVK GQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL
Predicted Disorder Regions	1-32, 276-319, 333-384
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Dong, X., Han, Y., Zhang, E., Wang, Y., Zhang, P., Wang, C., Zhong, L., & Li, Q. (2021). Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma. Aging, 13(7), 10603–10618. https://doi.org/10.18632/aging.202823