Search by BoMiProt ID - Bomi4988

Primary Information

BoMiProt ID Bomi4988
Protein Name Cytochrome c oxidase subunit 6B1/Cytochrome c oxidase polypeptide VII/Cytochrome c oxidase subunit AED
Organism Bos taurus
Uniprot IDP00429
Milk FractionWhey
Ref Sequence ID NP_788848.1
Aminoacid Length 86
Molecular Weight 10156
FASTA Sequence Download
Gene Name COX6B1
Gene ID 100270792
Protein Existence Status Reviewed

Secondary Information

Protein Function Cox6b1 is involved in regulation of mitochondrial function by promoting the formation of SC(supercomplexes), suggesting that Cox6b1 contributes to the anti-aging effects of CR(Calorie restriction).
PTMs N-acetylalanine,Disulfide bond formation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
SCOP Class : All alpha proteins
Fold : Cytochrome c oxidase subunit h
Superfamily : Cytochrome c oxidase subunit h
Family : Cytochrome c oxidase subunit h
Domain Name : 1V54 H:7-85

CATH Matched CATH superfamily
Predicted Disorder Regions 1-28, 74-86
DisProt Annotation
TM Helix Prediction No TM helices
PDB ID 1OCC, 1OCO, 1OCR, 1OCZ, 1V54, 1V55, 2DYR, 2DYS, 2EIJ, 2EIK, 2EIL, 2EIM, 2EIN, 2OCC, 2Y69, 2YBB, 2ZXW, 3ABK, 3ABL, 3ABM, 3AG1, 3AG2, 3AG3, 3AG4, 3AGN, 3ASO,3WG7, 3X2Q, 5B1A, 5B1B, 5B3S, 5GPN, 5IY5, 5LUF, 5W97, 5WAU, 5X19, 5X1B, 5X1F, 5XDQ, 5XDX, 5XTH, 5XTI, 5Z84, 5Z85, 5Z86, 5ZCO, 5ZCP, 5ZCQ, 6J8M, 6JUW, 6JY3, 6JY4, 6NKN, 6NMF, 6NMP, 7COH, 7CP5, 7D5W, 7D5X, 7EV7,
Bibliography 1.Kim SE, Mori R, Komatsu T, Chiba T, Hayashi H, Park S, Sugawa MD, Dencher NA, Shimokawa I. Upregulation of cytochrome c oxidase subunit 6b1 (Cox6b1) and formation of mitochondrial supercomplexes: implication of Cox6b1 in the effect of calorie restriction. Age (Dordr). 2015 Jun;37(3):9787. doi: 10.1007/s11357-015-9787-8. Epub 2015 May 1. PMID: 25929654; PMCID: PMC4416092. 2.Tanaka M, Yasunobu KT, Wei YH, King TE. The complete amino acid sequence of bovine heart cytochrome oxidase subunit VI. J Biol Chem. 1981 May 25;256(10):4832-7. PMID: 6262305.