Primary Information |
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| BoMiProt ID | Bomi4968 |
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| Protein Name | Cysteine and histidine-rich domain-containing protein 1/CHORD domain-containing protein 1 |
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| Organism | Bos taurus |
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| Uniprot ID | Q29RL2 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001039377.1 |
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| Aminoacid Length | 332 |
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| Molecular Weight | 37427 |
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| FASTA Sequence |
Download |
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| Gene Name | CHORDC1 |
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| Gene ID | 505144 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | Morgana/CHP-1 is a ubiquitously expressed protein able to inhibit ROCK II kinase activity. |
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| PTMs | N-Acetylation at Ala,Phosphorylation at Ser |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q29RL2|CHRD1_BOVIN Cysteine and histidine-rich domain-containing protein 1 OS=Bos taurus OX=9913 GN=CHORDC1 PE=2 SV=1
MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRT*47TDFS*51DFLSIVGCT
KGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLEL
KISASLKQALDKLKLSSGNEENKKEEDSDEIKIGTSCKNGGCSKTYQGPQSLEEVCVYHS
GVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTTGKHMWTKKDAGKKVVPCRHDWHQTGGE
VTISVYAKNSLPELSQVVANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKI
EITMRKAEPMQWASLELPAAKTEEKQKEETTE
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| Predicted Disorder Regions | 16-29, 61-154, 216-227, 313-332 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Fusella F, Ferretti R, Recupero D, Rocca S, Di Savino A, Tornillo G, Silengo L, Turco E, Cabodi S, Provero P, Pandolfi PP, Sapino A, Tarone G, Brancaccio M. Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway. J Pathol. 2014 Oct;234(2):152-63. doi: 10.1002/path.4341. Epub 2014 Aug 6. PMID: 24615293. |
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