Primary Information
BoMiProt ID	Bomi4943
Protein Name	C-X-C motif chemokine 17/VEGF coregulated chemokine 1
Organism	Bos taurus
Uniprot ID	A4IFR0
Milk Fraction	Whey
Ref Sequence ID	NP_001077268.1
Aminoacid Length	118
Molecular Weight	13597
FASTA Sequence	Download
Gene Name	CXCL17/VCC1
Gene ID	788717
Protein Existence Status	reviewed
Secondary Information
Protein Function	Acts as chemoattractant for cells such as monocytes, macrophages and dendritic cells (Chemokine). Plays a role in angiogenesis. May also have role in the tumorigenesis. May have a potential role in the innate defense against infections.
Biochemical Properties	Activates the C-X-C chemokine receptor GPR35 to induce a quick and shortlived increase in the level of intracellular calcium ions.
Significance in milk	plays an important role in the bovine mammary gland immunity
PTMs	Disulphide bond
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	2 disordered segments; (22-42), (72-100)
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Zimin, A. V., Delcher, A. L., Florea, L., Kelley, D. R., Schatz, M. C., Puiu, D., Hanrahan, F., Pertea, G., Van Tassell, C. P., Sonstegard, T. S., Marçais, G., Roberts, M., Subramanian, P., Yorke, J. A., & Salzberg, S. L. (2009). A whole-genome assembly of the domestic cow, Bos taurus. Genome biology, 10(4), R42. https://doi.org/10.1186/gb-2009-10-4-r42