Primary Information
BoMiProt ID	Bomi4792
Protein Name	Coiled-coil domain-containing protein 106
Organism	Bos taurus
Uniprot ID	Q1LZ89
Milk Fraction	whey
Ref Sequence ID	NP_001073803.1
Aminoacid Length	278
Molecular Weight	31387
FASTA Sequence	Download
Gene Name	CCDC106
Gene ID	618485
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Promotes the degradation of p53/TP53 protein and inhibits its transactivity.
Biochemical Properties	contains a bipartite nuclear localization signal
PTMs	Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q1LZ89|CC106_BOVIN Coiled-coil domain-containing protein 106 OS=Bos taurus OX=9913 GN=CCDC106 PE=2 SV=1 MNSRRRPVKKDSEALEISIPFDETPHLDPQIFYSLSPSRGNFEEPSEAASPTAALMNGVR AQLHLALERNSWLQKRIEDLEEERDFLRCQLDKFISSARLDADDHCRGKPGPRRAEGDGR GGTGGEAS*128DPESAASSLSGASEEGSTVERKRQKQKGGPGRRRFGKPKARERQRVKDADGV LCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKER LLEYSRRCFLALDEETLKKVQALKKSKLLLPITYRFKR
Predicted Disorder Regions	1-60, 74-76, 98-173
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Zhang, X., Zheng, Q., Wang, C., Zhou, H., Jiang, G., Miao, Y., Zhang, Y., Liu, Y., Li, Q., Qiu, X., & Wang, E. (2017). CCDC106 promotes non-small cell lung cancer cell proliferation. Oncotarget, 8(16), 26662–26670. https://doi.org/10.18632/oncotarget.15792