Search by BoMiProt ID - Bomi4753

Primary Information

BoMiProt ID Bomi4753
Protein Name Coatomer subunit beta/Beta-coat protein/Beta-COP
Organism Bos taurus
Uniprot IDA0JN39
Milk FractionWhey,MFGM
Ref Sequence ID NP_001071475.1
Aminoacid Length 953
Molecular Weight 107127
FASTA Sequence Download
Gene Name COPB1
Gene ID 535533
Protein Existence Status reviewed

Secondary Information

Protein Function Involved in intracellular protein transport and intra-golgi vesicle-mediated transport.OSBPL2 links the endoplasmic reticulum (ER) with LDs, binds to COPB1, and mediates ATGL transport.
Biochemical Properties It is a subunit of the COPI complex, is predicted to contain the AP-2 domain.
PTMs Proteolytic cleavage,Acetylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs Proteolytically cleaved between Ser-528 and Ser-529 by CAPN8.
Bibliography Wang T, Wei Q, Liang L, Tang X, Yao J, Lu Y, Qu Y, Chen Z, Xing G, Cao X. OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis. iScience. 2020 Jul 24;23(7):101252. doi: 10.1016/j.isci.2020.101252. Epub 2020 Jun 20. PMID: 32650117; PMCID: PMC7348002.