Primary Information |
|---|
| BoMiProt ID | Bomi4753 |
|---|
| Protein Name | Coatomer subunit beta/Beta-coat protein/Beta-COP |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | A0JN39 |
|---|
| Milk Fraction | Whey,MFGM |
|---|
| Ref Sequence ID | NP_001071475.1 |
|---|
| Aminoacid Length | 953 |
|---|
| Molecular Weight | 107127 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | COPB1 |
|---|
| Gene ID | 535533 |
|---|
| Protein Existence Status | reviewed |
|---|
Secondary Information |
|---|
| Protein Function | Involved in intracellular protein transport and intra-golgi vesicle-mediated transport.OSBPL2 links the endoplasmic reticulum (ER) with LDs, binds to COPB1, and mediates ATGL transport. |
|---|
| Biochemical Properties | It is a subunit of the COPI complex, is predicted to contain the AP-2 domain. |
|---|
| PTMs | Proteolytic cleavage,Acetylation |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
|---|
| Predicted Disorder Regions | NA |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | No TM helices |
|---|
| Significance of PTMs | Proteolytically cleaved between Ser-528 and Ser-529 by CAPN8. |
|---|
| Bibliography | Wang T, Wei Q, Liang L, Tang X, Yao J, Lu Y, Qu Y, Chen Z, Xing G, Cao X. OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis. iScience. 2020 Jul 24;23(7):101252. doi: 10.1016/j.isci.2020.101252. Epub 2020 Jun 20. PMID: 32650117; PMCID: PMC7348002. |
|---|
