Primary Information |
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| BoMiProt ID | Bomi4586 |
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| Protein Name | Cell death activator CIDE-B/Cell death-inducing DFFA-like effector B |
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| Organism | Bos taurus |
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| Uniprot ID | Q3T191 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001029739.1 |
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| Aminoacid Length | 219 |
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| Molecular Weight | 24650 |
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| FASTA Sequence |
Download |
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| Gene Name | CIDEB |
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| Gene ID | 528834 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | role in apoptosis.CIDE-B mediates cytochromec release from mitochondria and caspase 3 activity |
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| Biochemical Properties | strong cell death-inducing activity in its C-terminal domain. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | 1-4, 26-43, 118-126, 211-219 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Erdtmann L, Franck N, Lerat H, Le Seyec J, Gilot D, Cannie I, Gripon P, Hibner U, Guguen-Guillouzo C. The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis. J Biol Chem. 2003 May 16;278(20):18256-64. doi: 10.1074/jbc.M209732200. Epub 2003 Feb 20. PMID: 12595532. |
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