Search by BoMiProt ID - Bomi4492

Primary Information

BoMiProt ID Bomi4492
Protein Name Casein kinase I isoform beta
Organism Bos taurus
Uniprot IDP35507
Milk FractionExosomes
Ref Sequence ID NP_001091628.1
Aminoacid Length 336
Molecular Weight 38754
FASTA Sequence Download
Gene Name CSNK1B
Gene ID 785423
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells uterine horn 
Protein Function Casein kinases utilizes acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins and articipates in Wnt signaling pathway.
Biochemical Properties belong to the serine/threonine kinase.The CK1β-isoform has only been found in cows.They differ in length and sequence of the N-terminal (9–76 amino acids) and especially the C-terminal (24–200 amino acids) non-catalytic domain . By this, the molecular weight of the various CK1 isoforms ranges from 37 kD (CK1α) up to 51 kD (CK1γ3). The C-terminal domain plays a crucial role in substrate specificity and in the regulation of kinase activity.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 1-10, 306-336
DisProt Annotation
TM Helix Prediction No TM helices