Search by BoMiProt ID - Bomi4281

Primary Information

BoMiProt ID Bomi4281
Protein Name Biogenesis of lysosome-related organelles complex 1 subunit 6/BLOC-1 subunit 6/Pallid protein homolog/Pallidin
Organism Bos taurus
Uniprot IDQ08DU8
Milk FractionWhey
Ref Sequence ID NP_001069793.1
Aminoacid Length 172
Molecular Weight 19546
FASTA Sequence Download
Gene ID 614408
Protein Existence Status Reviewed

Secondary Information

Protein Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. 
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 1-74, 119-172
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Ghiani, C. A., Starcevic, M., Rodriguez-Fernandez, I. A., Nazarian, R., Cheli, V. T., Chan, L. N., Malvar, J. S., de Vellis, J., Sabatti, C., & Dell'Angelica, E. C. (2010). The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth. Molecular psychiatry, 15(2), 115–215.