Primary Information |
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| BoMiProt ID | Bomi4271 |
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| Protein Name | Beta-soluble NSF attachment protein/N-ethylmaleimide-sensitive factor attachment protein beta |
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| Organism | Bos taurus |
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| Uniprot ID | P81126 |
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| Milk Fraction | Whey,Casein,MFGM |
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| Ref Sequence ID | NP_001039698.1 |
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| Aminoacid Length | 298 |
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| Molecular Weight | 33555 |
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| FASTA Sequence |
Download |
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| Gene Name | NAPB/SNAPB |
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| Gene ID | 517728 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | β-SNAP(synaptosomal proteins) is known to bind to the SNAP receptors and is therefore involved in the control of neurotransmitter release as well as in constitutive vesicular transport. |
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| Biochemical Properties | SNAPs recruit the N-ethylmaleimide-sensitive factor to the membrane after being bound to specific membrane receptors termed soluble N-ethylmaleimide sensitive factor attachment protein receptors (SNAREs), which is a prerequisite of membrane fusion. β-SNAP is a key functional partner with Vti1a, Vamp, Snap, Napa, Stx1a, Stx7, Stx5a, Bnip1, Ykt6 and Cplx1. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | 1-12, 288-298 |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | Lin Z, Zhao D, Wang Y, Zhao W, Yin X, Zhou X, Zhang Z, Yang L. Downregulation of β-Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein: Proteomics-Based Identification in Early-Stage Prion Disease. Neurodegener Dis. 2015;15(4):193-201. doi: 10.1159/000371553. Epub 2015 May 22. PMID: 26022183. |
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