Search by BoMiProt ID - Bomi4259

Primary Information

BoMiProt ID Bomi4259
Protein Name Beta-crystallin B1/Beta-B1 crystallin
Organism Bos taurus
Uniprot IDP07318
Milk FractionWhey
Ref Sequence ID NP_776951.1
Aminoacid Length 253
Molecular Weight 28144
FASTA Sequence Download
Gene Name CRYBB1
Gene ID 282205
Protein Existence Status reviewed

Secondary Information

Protein Function Crystallins are the dominant structural components of the vertebrate eye lens
Significance in milk bovine lens formation
PTMs Acetylation, Methylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 1-45, 51-54, 249-253
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs Specific cleavages in the N-terminal arm occur during lens maturation and give rise to truncated forms, leading to impaired oligomerization and protein insolubilization.
Bibliography Berbers, G. A., Hoekman, W. A., Bloemendal, H., de Jong, W. W., Kleinschmidt, T., & Braunitzer, G. (1984). Homology between the primary structures of the major bovine beta-crystallin chains. European journal of biochemistry, 139(3), 467–479.