Primary Information |
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BoMiProt ID | Bomi4258 |
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Protein Name | Beta-crystallin A2/Beta-A2 crystallin |
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Organism | Bos taurus |
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Uniprot ID | P26444 |
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Milk Fraction | Whey |
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Ref Sequence ID | NP_776949.1 |
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Aminoacid Length | 197 |
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Molecular Weight | 22231 |
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FASTA Sequence |
Download |
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Gene Name | CRYBA2 |
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Gene ID | 282203 |
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Protein Existence Status | reviewed |
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Secondary Information |
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Protein Function | Important for eye development and maintenance.structural components of the vertebrate eye lens. |
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Biochemical Properties | Homo/heterodimer, or complexes of higher-order.The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.also contain C terminal extension.Has a two-domain beta-structure, folded into four very similar Greek key motifs. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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Predicted Disorder Regions | (1-17) |
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DisProt Annotation | |
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TM Helix Prediction | No TM helices |
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Bibliography | 1.van Rens GL, Driessen HP, Nalini V, Slingsby C, de Jong WW, Bloemendal H. Isolation and characterization of cDNAs encoding beta A2- and beta A4-crystallins: heterologous interactions in the predicted beta A4-beta B2 heterodimer. Gene. 1991 Jun 30;102(2):179-88. doi: 10.1016/0378-1119(91)90076-n. PMID: 1874445. |