Primary Information |
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| BoMiProt ID | Bomi4258 |
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| Protein Name | Beta-crystallin A2/Beta-A2 crystallin |
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| Organism | Bos taurus |
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| Uniprot ID | P26444 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_776949.1 |
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| Aminoacid Length | 197 |
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| Molecular Weight | 22231 |
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| FASTA Sequence |
Download |
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| Gene Name | CRYBA2 |
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| Gene ID | 282203 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Important for eye development and maintenance.structural components of the vertebrate eye lens. |
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| Biochemical Properties | Homo/heterodimer, or complexes of higher-order.The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.also contain C terminal extension.Has a two-domain beta-structure, folded into four very similar Greek key motifs. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | (1-17) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.van Rens GL, Driessen HP, Nalini V, Slingsby C, de Jong WW, Bloemendal H. Isolation and characterization of cDNAs encoding beta A2- and beta A4-crystallins: heterologous interactions in the predicted beta A4-beta B2 heterodimer. Gene. 1991 Jun 30;102(2):179-88. doi: 10.1016/0378-1119(91)90076-n. PMID: 1874445. |