Search by BoMiProt ID - Bomi4258

Primary Information

BoMiProt ID Bomi4258
Protein Name Beta-crystallin A2/Beta-A2 crystallin
Organism Bos taurus
Uniprot IDP26444
Milk FractionWhey
Ref Sequence ID NP_776949.1
Aminoacid Length 197
Molecular Weight 22231
FASTA Sequence Download
Gene Name CRYBA2
Gene ID 282203
Protein Existence Status reviewed

Secondary Information

Protein Function Important for eye development and maintenance.structural components of the vertebrate eye lens.
Biochemical Properties Homo/heterodimer, or complexes of higher-order.The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.also contain C terminal extension.Has a two-domain beta-structure, folded into four very similar Greek key motifs.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions (1-17)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.van Rens GL, Driessen HP, Nalini V, Slingsby C, de Jong WW, Bloemendal H. Isolation and characterization of cDNAs encoding beta A2- and beta A4-crystallins: heterologous interactions in the predicted beta A4-beta B2 heterodimer. Gene. 1991 Jun 30;102(2):179-88. doi: 10.1016/0378-1119(91)90076-n. PMID: 1874445.