Search by BoMiProt ID - Bomi4152

Primary Information

BoMiProt ID Bomi4152
Protein Name ATPase family AAA domain-containing protein 3
Organism Bos taurus
Uniprot IDA7YWC4
Milk FractionWhey
Ref Sequence ID NP_001098932.1
Aminoacid Length 586
Molecular Weight 66107
FASTA Sequence Download
Gene Name ATAD3
Gene ID 784353
Protein Existence Status reviewed

Secondary Information

Protein Function mitochondrial protein synthesis and participate in mitochondrial DNA replication..
Biochemical Properties a conserved C-terminal AAA+-ATPase domain (residues 320–518) that is present in flies, worms and mammals, characterized by ATP-binding and ATPase domains (Walker A and Walker B), including an SRH motif, sensor I and sensor II residues, and an arginine finger.
Significance in milk regulates milk biosynthesis and proliferation of mammary epithelial cells
PTMs Acetylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 12-43, 137-149, 570-586
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography Baudier J. ATAD3 proteins: brokers of a mitochondria-endoplasmic reticulum connection in mammalian cells. Biol Rev Camb Philos Soc. 2018 May;93(2):827-844. doi: 10.1111/brv.12373. Epub 2017 Sep 20. PMID: 28941010.