Search by BoMiProt ID - Bomi4142

Primary Information

BoMiProt ID Bomi4142
Protein Name ATP synthase subunit O, mitochondrial/ATP synthase peripheral stalk subunit OSCP/Oligomycin sensitivity conferral protein/ OSCP
Organism Bos taurus
Uniprot IDP13621
Milk Fractionwhey
Ref Sequence ID NP_776669.1
Aminoacid Length 213
Molecular Weight 23320
FASTA Sequence Download
Gene Name ATP5PO/ATP5O
Protein Existence Status Reviewed

Secondary Information

Protein Function Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain
PTMs Acetylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
CATH Matched CATH superfamily
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Significance of PTMs Acetylation at Lys-162 decreases ATP production. Deacetylated by SIRT3
Bibliography Walker, J. E., Gay, N. J., Powell, S. J., Kostina, M., & Dyer, M. R. (1987). ATP synthase from bovine mitochondria: sequences of imported precursors of oligomycin sensitivity conferral protein, factor 6, and adenosinetriphosphatase inhibitor protein. Biochemistry, 26(26), 8613–8619.