Primary Information |
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| BoMiProt ID | Bomi4131 |
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| Protein Name | ATP synthase F(0) complex subunit C3, mitochondrial/ATP synthase membrane subunit c locus 3/ATP synthase proteolipid P3/ATPase protein 9/ATPase subunit c |
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| Organism | Bos taurus |
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| Uniprot ID | Q3ZC75 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001029864.1 |
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| Aminoacid Length | 141 |
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| Molecular Weight | 14693 |
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| FASTA Sequence |
Download |
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| Gene Name | ATP5MC3 |
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| Gene ID | 540176 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | participate in electron transport chain |
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| Biochemical Properties | F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c |
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| PTMs | Acetylation on Lys and phosphorylation on Ser and Tyr |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | 2TMHs ;(80-102) & (117-139) |
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| Significance of PTMs | Trimethylated by ATPSCKMT at Lys-109. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. |
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| Additional Comments | This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease). |
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