Primary Information
BoMiProt ID	Bomi3781
Protein Name	Akirin-2
Organism	Bos taurus
Uniprot ID	A8YXY8
Milk Fraction	whey
Ref Sequence ID	NP_001103557.1
Aminoacid Length	203
Molecular Weight	22510
FASTA Sequence	Download
Gene Name	AKIRIN2
Gene ID	614292
Protein Existence Status	Reviewed
Secondary Information
Protein Function	It is required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1
PTMs	Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|A8YXY8|AKIR2_BOVIN Akirin-2 OS=Bos taurus OX=9913 GN=AKIRIN2 PE=2 SV=1 MACGATLKRTLDFDPLLS*18PAS*21PKRRRCAPLSAPTSAAATPSSAAAATAASFSAAAAS*57PQK YLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFLL SGPASPGTPSGTSSPLKKEQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYD AFVKFTHDQIMRRYGEQPASYVS
Predicted Disorder Regions	1-142, 189-203
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Karabay, A. Z., Koc, A., Ozkan, T., Hekmatshoar, Y., Altinok Gunes, B., Sunguroglu, A., Buyukbingol, Z., Atalay, A., & Aktan, F. (2018). Expression analysis of Akirin-2, NFκB-p65 and β-catenin proteins in imatinib resistance of chronic myeloid leukemia. Hematology (Amsterdam, Netherlands), 23(10), 765–770. https://doi.org/10.1080/10245332.2018.1488795