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Primary Information | |
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| BoMiProt ID | Bomi3742 |
| Protein Name | ADP-ribosylation factor-like protein 6 |
| Organism | Bos taurus |
| Uniprot ID | Q0IIM2 |
| Milk Fraction | Whey,MFGM |
| Ref Sequence ID | NP_001069250.1 |
| Aminoacid Length | 186 |
| Molecular Weight | 21055 |
| FASTA Sequence | Download |
| Gene Name | ARL6 |
| Gene ID | 519014 |
| Protein Existence Status | reviewed |
Secondary Information | |
| Protein Function | membrane protein trafficking. proper retinal function and organization. role in cilia or flagella function. Role in Early embryonic development.ARF-6 regulates the actin cytoskeletal organization by binding the Rac1-interacting protein POR1 in a GTP-dependent manner |
| Biochemical Properties | subfamily of the Arf family of small GTPases. |
| PTMs | N-myristoylation on glycine |
| Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | na |
| CATH | Matched CATH superfamily n/a |
| Predicted Disorder Regions | 1 disordered segment; (8-14) |
| DisProt Annotation | |
| TM Helix Prediction | No TM helices |
| PDB ID | 6VBV,6VOA, |
| Bibliography | Ingley E, Williams JH, Walker CE, Tsai S, Colley S, Sayer MS, Tilbrook PA, Sarna M, Beaumont JG, Klinken SP. A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit. FEBS Lett. 1999 Oct 1;459(1):69-74. doi: 10.1016/s0014-5793(99)01188-6. PMID: 10508919. |