Search by BoMiProt ID - Bomi3740

Primary Information

BoMiProt ID Bomi3740
Protein Name ADP-ribosylation factor-like protein 4A
Organism Bos taurus
Uniprot IDQ3T0M9
Milk FractionWhey
Ref Sequence ID NP_001070453.1
Aminoacid Length 200
Molecular Weight 22588
FASTA Sequence Download
Gene Name ARL4A
Gene ID 767906
Protein Existence Status Reviewed

Secondary Information

Presence in other biological fluids/tissue/cells spermatid
Protein Function ADP-ribosylation factor (Arf)-like 4A (Arl4A), an Arf small GTPase, functions in cell morphology, cell migration, and actin cytoskeleton remodeling
PTMs Myristoylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments  Overexpression of Arl4A does not restore the reduced motility of Robo1-knockdown cells.
Bibliography 1.Chiang TS, Lin MC, Tsai MC, Chen CH, Jang LT, Lee FS. ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation. Mol Biol Cell. 2019 Jan 1;30(1):69-81. doi: 10.1091/mbc.E18-01-0001. Epub 2018 Nov 14. PMID: 30427759; PMCID: PMC6337904. 2.