Primary Information |
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| BoMiProt ID | Bomi3740 |
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| Protein Name | ADP-ribosylation factor-like protein 4A |
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| Organism | Bos taurus |
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| Uniprot ID | Q3T0M9 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001070453.1 |
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| Aminoacid Length | 200 |
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| Molecular Weight | 22588 |
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| FASTA Sequence |
Download |
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| Gene Name | ARL4A |
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| Gene ID | 767906 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | spermatid |
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| Protein Function | ADP-ribosylation factor (Arf)-like 4A (Arl4A), an Arf small GTPase, functions in cell morphology, cell migration, and actin cytoskeleton remodeling |
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| PTMs | Myristoylation |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Additional Comments | Overexpression of Arl4A does not restore the reduced motility of Robo1-knockdown cells. |
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| Bibliography | 1.Chiang TS, Lin MC, Tsai MC, Chen CH, Jang LT, Lee FS. ADP-ribosylation factor-like 4A interacts with Robo1 to promote cell migration by regulating Cdc42 activation. Mol Biol Cell. 2019 Jan 1;30(1):69-81. doi: 10.1091/mbc.E18-01-0001. Epub 2018 Nov 14. PMID: 30427759; PMCID: PMC6337904. 2. |
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