Primary Information
BoMiProt ID	Bomi3739
Protein Name	ADP-ribosylation factor-like protein 1
Organism	Bos taurus
Uniprot ID	Q2YDM1
Milk Fraction	Whey,Exosome,MFGM
Ref Sequence ID	NP_001039694.1
Aminoacid Length	181
Molecular Weight	20428
FASTA Sequence	Download
Gene Name	ARL1
Gene ID	517345
Protein Existence Status	Reviewed
Secondary Information
Protein Function	Arl1 is essential for formation of secretory granules in the larval salivary gland.It is a GTP-binding protein. It can activate phospholipase D (PLD) as well but with reduced efficiency. It is also important for normal function of the Golgi apparatus.Arl1 is required for secretory granule maturation.
Biochemical Properties	The GTP-bound form interacts with GOLGA1, GOLGA4 and RGPD8. The GTP-bound form directly interacts with ARFIP2; this interaction leads to an increase in the amount of bound GTP at steady state level. Binds to SCOC, preferentially in its GTP-bound form. May interact with UNC119
PTMs	Myristoylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Lee, F. J., Huang, C. F., Yu, W. L., Buu, L. M., Lin, C. Y., Huang, M. C., Moss, J., & Vaughan, M. (1997). Characterization of an ADP-ribosylation factor-like 1 protein in Saccharomyces cerevisiae. The Journal of biological chemistry, 272(49), 30998–31005. https://doi.org/10.1074/jbc.272.49.30998