Primary Information |
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| BoMiProt ID | Bomi3700 |
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| Protein Name | Adenylosuccinate synthetase isozyme 1 |
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| Organism | Bos taurus |
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| Uniprot ID | A5PJR4 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001092662.1 |
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| Aminoacid Length | 457 |
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| Molecular Weight | 50134 |
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| FASTA Sequence |
Download |
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| Gene Name | ADSS1 |
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| Gene ID | 784089 |
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| Protein Existence Status | reviewed |
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Secondary Information |
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| Protein Function | Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
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| Biochemical Properties | Cofactor is Mg2+.Utilises asparatate as substrate. Catalyses the following reaction-GTP + IMP + L-aspartate = GDP + 2 H+ + N6-(1,2-dicarboxyethyl)-AMP + phosphate. |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | (1-25) |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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