Primary Information |
---|
BoMiProt ID | Bomi3626 |
---|
Protein Name | Actin-related protein 2/3 complex subunit 1A |
---|
Organism | Bos taurus |
---|
Uniprot ID | Q1JP79 |
---|
Milk Fraction | Exosomes,MFGM |
---|
Ref Sequence ID | NP_001068827.1 |
---|
Aminoacid Length | 370 |
---|
Molecular Weight | 41539 |
---|
FASTA Sequence |
Download |
---|
Gene Name | ARPC1A |
---|
Gene ID | 508402 |
---|
Protein Existence Status | Reviewed |
---|
Secondary Information |
---|
Presence in other biological fluids/tissue/cells | thyroid gland |
---|
Protein Function | Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
---|
Biochemical Properties | Arp2/3 (actin-related protein 2/3) complex is a seven-subunit complex that nucleates branched actin filaments in response to cellular signals. Nucleation-promoting factors such as WASp/Scar family proteins activate the complex by facilitating the activating conformational change and recruiting the first actin monomer for the daughter branch. |
---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
---|
Predicted Disorder Regions | NA |
---|
DisProt Annotation | |
---|
TM Helix Prediction | No TM helices |