Search by BoMiProt ID - Bomi3521


Primary Information

BoMiProt ID Bomi3521
Protein Name 40S ribosomal protein S4
Organism Bos taurus
Uniprot IDP79103
Milk FractionWhey
Ref Sequence ID NP_001030522.1
Aminoacid Length 263
Molecular Weight 29598
FASTA Sequence Download
Gene Name RPS4
Gene ID 614241
Protein Existence Status reviewed

Secondary Information

Protein Function a 40S ribosomal protein S4-derived H-Y epitope able to elicit a lymphoblast-specific cytotoxic T lymphocyte response
Biochemical Properties  The deduced amino acid sequence shares 96% and 91% identity with RPS4 genes from Aedes and Anopheles respectively. 
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
na
Predicted Disorder Regions 1-17, 256-263
DisProt Annotation
TM Helix Prediction No TM helices
Additional Comments Diseases associated with RPS4X include Turner Syndrome and Disorder Of Sexual Development. Among its related pathways are HIV Life Cycle and Viral mRNA Translation. 
Bibliography 1.Hu X, Wang W, Zhang D, Jiao J, Tan W, Sun Y, Ma L, Zhu C. Cloning and characterization of 40S ribosomal protein S4 gene from Culex pipiens pallens. Comp Biochem Physiol B Biochem Mol Biol. 2007 Feb;146(2):265-70. doi: 10.1016/j.cbpb.2006.11.011. Epub 2006 Nov 25. PMID: 17196859. 2.Ivanov R, Aarts T, Hol S, Doornenbal A, Hagenbeek A, Petersen E, Ebeling S. Identification of a 40S ribosomal protein S4-derived H-Y epitope able to elicit a lymphoblast-specific cytotoxic T lymphocyte response. Clin Cancer Res. 2005 Mar 1;11(5):1694-703. doi: 10.1158/1078-0432.CCR-04-1772. PMID: 15755990.