Search by BoMiProt ID - Bomi3493

Primary Information

BoMiProt ID Bomi3493
Protein Name 39S ribosomal protein L22, mitochondrial
Organism Bos taurus
Uniprot IDQ3SZX5
Milk FractionWhey
Ref Sequence ID NP_001030531.1
Aminoacid Length 204
Molecular Weight 23552
FASTA Sequence Download
Gene Name MRPL22/L22mt
Gene ID 614639
Protein Existence Status reviewed

Secondary Information

Protein Function ribosome assembly
Biochemical Properties PI value of phosphorylated Bovine Mitochondrial Ribosomal Protein is 9.87.Size.Mol wt is 24.2kDa.A deletion of Met82-Lys83-Arg84 in bacterial L22 leads to erythromycin resistance inhibiting peptide chain elongation.Several Ser, Thr, and Tyr residues are clustered in close proximity to the conserved Lys83-Arg84 in bacteria resulting in erythromycin resistance.
PTMs Ubl conjugation at Lys191
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
SCOP Class : Alpha and beta proteins (a/b)
Fold : 50S Ribosomal protein L22
Superfamily : Ribosomal protein L22
Family : Ribosomal protein L22
Domain Name : 2FTC M:1-110

CATH Matched CATH superfamily
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction no TM helices
Bibliography 1.Miller, J. L., Cimen, H., Koc, H., & Koc, E. C. (2009). Phosphorylated proteins of the mammalian mitochondrial ribosome: implications in protein synthesis. Journal of proteome research, 8(10), 4789–4798. 2.Suzuki, T., Terasaki, M., Takemoto-Hori, C., Hanada, T., Ueda, T., Wada, A., & Watanabe, K. (2001). Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. The Journal of biological chemistry, 276(24), 21724–21736.