Primary Information
BoMiProt ID	Bomi328
Protein Name	Solute carrier family 22 (Organic cation/carnitine transporter), member 5
Organism	Bos taurus
Uniprot ID	Q2KJE9
Milk Fraction	Exosome
Ref Sequence ID	NP_001039967.1
Aminoacid Length	557
Molecular Weight	62826
FASTA Sequence	Download
Gene Name	SLC22A5
Gene ID	541266
Protein Existence Status	Unreviewed: Experimental evidence at transcript level
Secondary Information
Presence in other biological fluids/tissue/cells	present in kidney and liver, brain, placenta, intestine, and lung
Protein Function	operate as transporters for organic cations (OCTs), organic cations and zwitterions (OCTNs) or organic anions; play a pivotal role in the secretion of organic ions; contribute to the homeostasis of organic ions; polyspecific transporters as they are able to transport structurally different compounds
Significance in milk	nutrient transport systems for milk precursors and constituents
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation
Bibliography	1. Anzai, N., Jutabha, P., Enomoto, A., Yokoyama, H., Nonoguchi, H., Hirata, T., … Endou, H. (2005). Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules. The Journal of Pharmacology and Experimental Therapeutics, 315(2), 534–544. https://doi.org/10.1124/jpet.105.088583. 2. Jacobsson, J. A., Haitina, T., Lindblom, J., & Fredriksson, R. (2007). Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. Genomics, 90(5), 595–609. https://doi.org/10.1016/j.ygeno.2007.03.017.