Primary Information |
|---|
| BoMiProt ID | Bomi3240 |
|---|
| Protein Name | Ubiquitin-40S ribosomal protein S27a |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | P62992 |
|---|
| Milk Fraction | Whey |
|---|
| Ref Sequence ID | NP_777203.1 |
|---|
| Aminoacid Length | 156 |
|---|
| Molecular Weight | 17965 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | RPS27A |
|---|
| Gene ID | 286839 |
|---|
| Protein Existence Status | Reviewed: Experimental evidence at protein level |
|---|
Secondary Information |
|---|
| Significance in milk | N6-Acetylation at Lys, ADP-ribosylation, Isopeptide bond formation,Phosphorylation at Serine, Ubl conjugation |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| |
|---|
| Predicted Disorder Regions | |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | No TM helices |
|---|
| Significance of PTMs | Phosphorylated ubiquitin specifically binds and activates parkin (PRKN), triggering mitophagy. ADP-ribosylation requires processing by E1 and E2 enzymes and prevents ubiquitin conjugation to substrates such as histones. |