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Primary Information | |
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| BoMiProt ID | Bomi3229 |
| Protein Name | Antithrombin-III |
| Organism | Bos taurus |
| Uniprot ID | P41361 |
| Milk Fraction | Whey |
| Ref Sequence ID | NP_001029870.1 |
| Aminoacid Length | 465 |
| Molecular Weight | 52347 |
| FASTA Sequence | Download |
| Gene Name | SERPINC1 |
| Gene ID | 540261 |
| Protein Existence Status | Reveiwed:Experimental evidence at protein level |
Secondary Information | |
| Protein Function | Antithrombin III plays many different roles during cardiac operations with cardiopulmonary bypass. Basically, it acts as the natural inhibitor of thrombin, which, in presence of heparin, blocks the thrombin action and avoids gross thrombus formation inside the extracorporeal circulation circuit. |
| Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | |
| Predicted Disorder Regions | NA |
| DisProt Annotation | |
| TM Helix Prediction | No TM helices |
| PDB ID | 1ATT, |
| Bibliography | 1.Ranucci M. Antithrombin III. Key factor in extracorporeal circulation. Minerva Anestesiol. 2002 May;68(5):454-7. PMID: 12029263. |