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Primary Information | |
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| BoMiProt ID | Bomi2785 |
| Protein Name | Tektin-1 |
| Organism | Bos taurus |
| Uniprot ID | Q32KZ9 |
| Milk Fraction | MFGM, Exosome |
| Ref Sequence ID | NP_001069251.1 |
| Aminoacid Length | 418 |
| Molecular Weight | 48719 |
| FASTA Sequence | Download |
| Gene Name | TEKT1 |
| Gene ID | 519068 |
| Protein Existence Status | Reveiwed:Experimental evidence at transcript level |
Secondary Information | |
| Presence in other biological fluids/tissue/cells | found throughout the eukaryotes apart from higher plants |
| Protein Function | Essential for the construction of cilia and flagella; related to intermediate filament (IF) proteins and nuclear lamins; presence of longitudinal repeating pattern of hydrophobic and charged amino acids |
| Biochemical Properties | Insoluble α-helical proteins; variable amino- and carboxy-terminal head and tail domains |
| Linking IDs | Bomi87 |
| Bibliography | 1. Linck, R. W. (1976). Flagellar doublet microtubules: fractionation of minor components and alpha-tubulin from specific regions of the A-tubule. Journal of Cell Science, 20(2), 405–439. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/1262413. 2. Norrander, J. M., Amos, L. A., & Linck, R. W. (1992). Primary structure of tektin A1: comparison with intermediate-filament proteins and a model for its association with tubulin. Proceedings of the National Academy of Sciences of the United States of America, 89(18), 8567–8571. https://doi.org/10.1073/pnas.89.18.8567. 3. McLachlan, A. D., & Stewart, M. (1982). Periodic charge distribution in the intermediate filament proteins desmin and vimentin. Journal of Molecular Biology, 162(3), 693–698. https://doi.org/10.1016/0022-2836(82)90396-5. 4. Parry, D. A. D., Strelkov, S. V, Burkhard, P., Aebi, U., & Herrmann, H. (2007). Towards a molecular description of intermediate filament structure and assembly. Experimental Cell Research, 313(10), 2204–2216. https://doi.org/10.1016/j.yexcr.2007.04.009. |
| Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation | |
| Predicted Disorder Regions | (399-418) |
| DisProt Annotation | |
| TM Helix Prediction | No TM helices |