Search by BoMiProt ID - Bomi2704


Primary Information

BoMiProt ID Bomi2704
Protein Name Ribonuclease pancreatic
Organism Bos taurus
Uniprot IDP61823
Milk FractionWhey, Exosome
Ref Sequence ID NP_001014408.2
Aminoacid Length 150
Molecular Weight 16461
FASTA Sequence Download
Gene Name RNASE1
Gene ID 282340
Protein Existence Status Reveiwed:Experimental evidence at protein level

Secondary Information

Protein Function Bovine pancreatic ribonuclease A is an enzyme that catalyses the depolymerization of RNA.The enzyme shows a strong specificity for pyrimidine bases at the 3'-position of the phosphodiester bond that is cleaved and a preference for purine bases at the 5'-position and, probably, for guanine at the next position.
PTMs Disulfide bond formation, Glycation,N-Linked Glycosylation at Asn
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Phosphorylation
Predicted Disorder Regions NA
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1.Nogués MV, Vilanova M, Cuchillo CM. Bovine pancreatic ribonuclease A as a model of an enzyme with multiple substrate binding sites. Biochim Biophys Acta. 1995 Nov 15;1253(1):16-24. doi: 10.1016/0167-4838(95)00138-k. PMID: 7492594. 2.SMYTH DG, STEIN WH, MOORE S. The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations. J Biol Chem. 1963 Jan;238:227-34. PMID: 13989651.