Primary Information |
|---|
| BoMiProt ID | Bomi2704 |
|---|
| Protein Name | Ribonuclease pancreatic |
|---|
| Organism | Bos taurus |
|---|
| Uniprot ID | P61823 |
|---|
| Milk Fraction | Whey, Exosome |
|---|
| Ref Sequence ID | NP_001014408.2 |
|---|
| Aminoacid Length | 150 |
|---|
| Molecular Weight | 16461 |
|---|
| FASTA Sequence |
Download |
|---|
| Gene Name | RNASE1 |
|---|
| Gene ID | 282340 |
|---|
| Protein Existence Status | Reveiwed:Experimental evidence at protein level |
|---|
Secondary Information |
|---|
| Protein Function | Bovine pancreatic ribonuclease A is an enzyme that catalyses the depolymerization of RNA.The enzyme shows a strong specificity for pyrimidine bases at the 3'-position of the phosphodiester bond that is cleaved and a preference for purine bases at the 5'-position and, probably, for guanine at the next position. |
|---|
| PTMs | Disulfide bond formation, Glycation,N-Linked Glycosylation at Asn |
|---|
Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| |
|---|
| Predicted Disorder Regions | NA |
|---|
| DisProt Annotation | |
|---|
| TM Helix Prediction | No TM helices |
|---|
| Bibliography | 1.Nogués MV, Vilanova M, Cuchillo CM. Bovine pancreatic ribonuclease A as a model of an enzyme with multiple substrate binding sites. Biochim Biophys Acta. 1995 Nov 15;1253(1):16-24. doi: 10.1016/0167-4838(95)00138-k. PMID: 7492594. 2.SMYTH DG, STEIN WH, MOORE S. The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations. J Biol Chem. 1963 Jan;238:227-34. PMID: 13989651. |
|---|
