Search by BoMiProt ID - Bomi2275

Primary Information

BoMiProt ID Bomi2275
Protein Name Rab GDP dissociation inhibitor alpha
Organism Bos taurus
Uniprot IDP21856
Milk FractionWhey, Exosome
Ref Sequence ID NP_776489.1
Aminoacid Length 447
Molecular Weight 50566
FASTA Sequence Download
Gene Name GDI1
Gene ID 281188
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondary Information

Protein Function Rab GDI alpha is a candidate autoantigen involved in IAD(Isolated adrenocorticotropin deficiency ), and that anti-Rab GDI alpha antibodies are present predominantly in patients with IAD.
PTMs Phosphorylation at serine
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 156-163,361-367,438-447
DisProt Annotation
TM Helix Prediction 1TMH; (7-25)
Bibliography 1.Kiyota A, Iwama S, Sugimura Y, Takeuchi S, Takagi H, Iwata N, Nakashima K, Suzuki H, Nishioka T, Kato T, Enomoto A, Arima H, Kaibuchi K, Oiso Y. Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency. Endocr J. 2015;62(2):153-60. doi: 10.1507/endocrj.EJ14-0369. Epub 2014 Oct 26. PMID: 25346144.