Primary Information |
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| BoMiProt ID | Bomi145 |
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| Protein Name | Alpha-1B-glycoprotein |
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| Organism | Bos taurus |
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| Uniprot ID | Q2KJF1 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001039708.1 |
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| Aminoacid Length | 503 |
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| Molecular Weight | 53554 |
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| FASTA Sequence |
Download |
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| Gene Name | A1BG |
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| Gene ID | 518955 |
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| Protein Existence Status | Reviewed: Experimental evidence at protein level |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | urine |
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| Protein Function | associated with bladder cancer, having been detected in all tumor-bearing patient samples; could be involved in cell recognition and the regulation of cell behavior |
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| Biochemical Properties | exhibits internal duplication and
consists of five repeating structural domains, each containing
about 95 amino acids and one disulfide bond.; |
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| Significance in milk | Helps in building immunity |
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| PTMs | single polypeptide chain N-linked to four
glucosamine oligosaccharides; All four glucosamine oligosaccharides
are attached to asparagine in the obligate tripeptide
acceptor sequence Asn-Xaa-Ser/Thr, in which Xaa is almost
any amino acid; five
intrachain disulfide bonds |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1. Ishioka, N., Takahashi, N., & Putnam, F. W. (1986). Amino acid sequence of human plasma alpha 1B-glycoprotein: homology to the immunoglobulin supergene family. Proceedings of the National Academy of Sciences of the United States of America, 83(8), 2363–2367. https://doi.org/10.1073/pnas.83.8.2363 |
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