Search by BoMiProt ID - Bomi143

Primary Information

BoMiProt ID Bomi143
Protein Name Carboxypeptidase B2
Organism Bos taurus
Uniprot IDQ2KIG3
Milk FractionWhey
Ref Sequence ID NP_001039462.1
Aminoacid Length 423
Molecular Weight 48822
FASTA Sequence Download
Gene Name CPB2
Gene ID 508222
Protein Existence Status Reviewed: Experimental evidence at protein level

Secondary Information

Protein Function enzyme that selectively catalyzes the release of the carboxyl-terminal basic amino acids, arginine and lysine, from proteins and peptides; possess esterase activity toward hippuryl-n-argininic acid
Biochemical Properties The inhibition of the enzyme by phosphate and that by citrate are pH-dependent and are most pronounced below pH 6.5; decreasing effectiveness as inhibitors at pH 8: NaI, KSCN, NaBr, MgS04, NaCI, KCl, and NaN03;
Significance in milk belong to the protease system in milk
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
SCOP Class : Alpha and beta proteins (a/b)
Fold : Phosphorylase/hydrolase-like
Superfamily : Zn-dependent exopeptidases
Family : Pancreatic carboxypeptidase-like
Domain Name : 3D4U A:7-308

CATH Matched CATH superfamily
Predicted Disorder Regions (1-117)
DisProt Annotation
TM Helix Prediction No TM helices
Bibliography 1. FOLK, J. E., WOLFF, E. C., & SCHIRMER, E. W. (1962). The kinetics of carboxypeptidase B activity. II. Kinetic parameters of the cobalt and cadmium enzymes. The Journal of Biological Chemistry, 237, 3100–3104. Retrieved from