Search by BoMiProt ID - Bomi10801

Primary Information

BoMiProt ID Bomi10801
Protein Name Zinc transporter ZIP13/Solute carrier family 39 member 13/Zrt- and Irt-like protein 13
Organism Bos taurus
Uniprot IDA5D7H1
Milk FractionWhey
Ref Sequence ID NP_001091601.1
Aminoacid Length 423
Molecular Weight 44432
FASTA Sequence Download
Gene Name SLC39A13/ZIP13
Gene ID 614946
Protein Existence Status reviewed

Secondary Information

Protein Function Zn2+ homeostasis and adipocyte biogenesis
Biochemical Properties ZIP13 contains eight putative transmembrane domains and a unique hydrophilic region and that it resides with both its N and C termini facing the luminal side on the Golgi.
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions 137-143, 176-189, 330-365
DisProt Annotation
TM Helix Prediction 5TMHs; (67-89),(110-132),(151-169),(371-389) and (404-422)
Additional Comments ZIP13 is downregulated at reperfusion in mouse hearts
Bibliography Wang J, Cheng X, Zhao H, Yang Q, Xu Z. Downregulation of the zinc transporter SLC39A13 (ZIP13) is responsible for the activation of CaMKII at reperfusion and leads to myocardial ischemia/reperfusion injury in mouse hearts. J Mol Cell Cardiol. 2021 Mar;152:69-79. doi: 10.1016/j.yjmcc.2020.12.002. Epub 2020 Dec 9. PMID: 33307093.