Primary Information
BoMiProt ID	Bomi10799
Protein Name	Zinc transporter ZIP1
Organism	Bos taurus
Uniprot ID	Q3SYU3
Milk Fraction	Whey
Ref Sequence ID	NP_001030458.1
Aminoacid Length	324
Molecular Weight	34205
FASTA Sequence	Download
Gene Name	SLC39A1
Protein Existence Status	reviewed
Secondary Information
Protein Function	It is involved in Zinc uptake mechanism and it may function as a zinc uptake transporter in different cell types.
PTMs	glycosylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	(1-5), (137-169)
DisProt Annotation
TM Helix Prediction	6TMHs; (33-51), (71-89) ,(108-126) ,(238-260), (279-297) & (304-322)
Significance of PTMs	In zinc-limited cells of yeast, ZRT1 is a stable, N-glycosylated plasma membrane protein.
Bibliography	1.Gitan RS, Luo H, Rodgers J, Broderius M, Eide D. Zinc-induced inactivation of the yeast ZRT1 zinc transporter occurs through endocytosis and vacuolar degradation. J Biol Chem. 1998 Oct 30;273(44):28617-24. doi: 10.1074/jbc.273.44.28617. PMID: 9786854. 2.Wang, P., Zhang, J., He, S., Xiao, B., & Peng, X. (2020). SLC39A1 contribute to malignant progression and have clinical prognostic impact in gliomas. Cancer cell international, 20(1), 573. https://doi.org/10.1186/s12935-020-01675-0