Search by BoMiProt ID - Bomi10799

Primary Information

BoMiProt ID Bomi10799
Protein Name Zinc transporter ZIP1
Organism Bos taurus
Uniprot IDQ3SYU3
Milk FractionWhey
Ref Sequence ID NP_001030458.1
Aminoacid Length 324
Molecular Weight 34205
FASTA Sequence Download
Gene Name SLC39A1
Protein Existence Status reviewed

Secondary Information

Protein Function It is involved in Zinc uptake mechanism and it may function as a zinc uptake transporter in different cell types.
PTMs glycosylation
Site(s) of PTM(s)

N-glycosylation, O-glycosylation,
Predicted Disorder Regions (1-5), (137-169)
DisProt Annotation
TM Helix Prediction 6TMHs; (33-51), (71-89) ,(108-126) ,(238-260), (279-297) & (304-322)
Significance of PTMs In zinc-limited cells of yeast, ZRT1 is a stable, N-glycosylated plasma membrane protein.
Bibliography 1.Gitan RS, Luo H, Rodgers J, Broderius M, Eide D. Zinc-induced inactivation of the yeast ZRT1 zinc transporter occurs through endocytosis and vacuolar degradation. J Biol Chem. 1998 Oct 30;273(44):28617-24. doi: 10.1074/jbc.273.44.28617. PMID: 9786854. 2.Wang, P., Zhang, J., He, S., Xiao, B., & Peng, X. (2020). SLC39A1 contribute to malignant progression and have clinical prognostic impact in gliomas. Cancer cell international, 20(1), 573.