Primary Information
BoMiProt ID	Bomi10646
Protein Name	YrdC domain-containing protein, mitochondrial
Organism	Bos taurus
Uniprot ID	Q0VC80
Milk Fraction	Whey
Ref Sequence ID	NP_001069018.1
Aminoacid Length	276
Molecular Weight	28893
FASTA Sequence	Download
Gene Name	YRDC
Gene ID	512062
Protein Existence Status	reviewed
Secondary Information
Protein Function	involved in the formation of threonylcarbamoyladenosine in transfer ribonucleic acid
Biochemical Properties	single domain.The protein contains a sua5-yciO-yrdC domain,a GTP-binding elongation factors signature (residues 229–241), and a leucine zipper pattern (residues 259–279).Leucine zipper pattern is related to protein dimerization and nucleic acid binding.YrdC binds preferentially to double-stranded RNA.
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	1-5, 22-60
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	1.Chen J, Ji C, Gu S, Zhao E, Dai J, Huang L, Qian J, Ying K, Xie Y, Mao Y. Isolation and identification of a novel cDNA that encodes human yrdC protein. J Hum Genet. 2003;48(4):164-9. doi: 10.1007/s10038-002-0001-3. Epub 2003 Mar 1. PMID: 12730717.2.Shen H, Zheng E, Yang Z, Yang M, Xu X, Zhou Y, Ni J, Li R, Zhao G. YRDC is upregulated in non-small cell lung cancer and promotes cell proliferation by decreasing cell apoptosis. Oncol Lett. 2020 Jul;20(1):43-52. doi: 10.3892/ol.2020.11560. Epub 2020 Apr 21. PMID: 32565932; PMCID: PMC7285791.