Primary Information
BoMiProt ID	Bomi10545
Protein Name	V-type proton ATPase subunit E 2/V-ATPase subunit E 2/Vacuolar proton pump subunit E 2
Organism	Bos taurus
Uniprot ID	Q32LB7
Milk Fraction	Whey
Ref Sequence ID	NP_001073081.1
Aminoacid Length	226
Molecular Weight	26171
FASTA Sequence	Download
Gene Name	ATP6V1E2
Gene ID	540113
Protein Existence Status	reviewed
Secondary Information
Protein Function	responsible for acidifying a variety of intracellular compartments in eukaryotic cells and to facilitate activation of SMPD1(sphingomyelin phosphodiesterase 1) and consequent MR(membrane rafts) aggregation.Together these have a potential role in lysosome fusion.
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	na
Predicted Disorder Regions	NA
DisProt Annotation
TM Helix Prediction	No TM helices
Bibliography	Han WQ, Xu L, Tang XF, Chen WD, Wu YJ, Gao PJ. Membrane rafts-redox signalling pathway contributes to renal fibrosis via modulation of the renal tubular epithelial-mesenchymal transition. J Physiol. 2018 Aug;596(16):3603-3616. doi: 10.1113/JP275952. Epub 2018 Jul 23. PMID: 29863758; PMCID: PMC6092309.