Primary Information
BoMiProt ID	Bomi10493
Protein Name	Voltage-dependent calcium channel gamma-3 subunit/Transmembrane AMPAR regulatory protein gamma-3/TARP gamma-3/Neuronal voltage-gated calcium channel gamma-3 subunit
Organism	Bos taurus
Uniprot ID	Q0VD05
Milk Fraction	Whey
Ref Sequence ID	NP_001071482.1
Aminoacid Length	315
Molecular Weight	35500
FASTA Sequence	Download
Gene Name	CACNG3
Gene ID	538496
Protein Existence Status	reviewed
Secondary Information
Protein Function	regulate both trafficking and channel gating of the AMPA receptors.
PTMs	Phosphorylation
Site(s) of PTM(s) N-glycosylation, O-glycosylation, Phosphorylation	>sp|Q0VD05|CCG3_BOVIN Voltage-dependent calcium channel gamma-3 subunit OS=Bos taurus OX=9913 GN=CACNG3 PE=2 SV=1 MRMCDRGVQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFY FGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSELLKKSTFARLPPYRYRFRRRSSSRST EPRSRDLS*248PISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFK ESLHNNPANRRTTPV
Predicted Disorder Regions	4 disordered segments; (47-51), (233-256), (277-280), (295-315)
DisProt Annotation
TM Helix Prediction	4TMHs ; (7-29), (105-127), (134-156), (179-201)
Bibliography	Everett KV, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Eeg-Olofsson O, Feucht M, Friis M, Goutieres F, Guerrini R, Heils A, Kjeldsen M, Lehesjoki AE, Makoff A, Nabbout R, Olsson I, Sander T, Sirén A, McKeigue P, Robinson R, Taske N, Rees M, Gardiner M. Linkage and association analysis of CACNG3 in childhood absence epilepsy. Eur J Hum Genet. 2007 Apr;15(4):463-72. doi: 10.1038/sj.ejhg.5201783. Epub 2007 Jan 31. Erratum in: Eur J Hum Genet. 2008 May;16(5):659-60. PMID: 17264864; PMCID: PMC2556708.