Primary Information |
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| BoMiProt ID | Bomi10482 |
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| Protein Name | Vesicle-associated membrane protein-associated protein A |
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| Organism | Bos taurus |
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| Uniprot ID | Q0VCY1 |
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| Milk Fraction | Whey |
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| Ref Sequence ID | NP_001069201.1 |
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| Aminoacid Length | 249 |
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| Molecular Weight | 27856 |
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| FASTA Sequence |
Download |
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| Gene Name | VAPA |
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| Gene ID | 516024 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Presence in other biological fluids/tissue/cells | gluteal muscle |
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| Protein Function | It is a syntaxin-like protein implicated in endoplasmic reticulum (ER)/Golgi vesicle transport, and phospholipid regulation in mammalian cells and yeast, respectively. |
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| PTMs | N-acetylation at Alanine,Phosphorylation at Serine |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| >sp|Q0VCY1|VAPA_BOVIN Vesicle-associated membrane protein-associated protein A OS=Bos taurus OX=9913 GN=VAPA PE=2 SV=1
MASASGTMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
VRPNSGIIDPGLTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNISDMEAVWKEAKPDE
LMDSKLRCVFEMPNENDKLNDMEPSKAVPLNAAKQDGPVPKPHSVS*166LSDT*170ETRKLVEECK
RLQGEMMKLSEENRLLRDEGLRLRKVAHSEKPGS*214TS*216AVS*219FRENVTSPLPSLLVVIAAIFI
GFFLGKFIL
|
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| Predicted Disorder Regions | 1-9, 131-172, 204-219 |
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| DisProt Annotation | |
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| TM Helix Prediction | 1TMH; (230-248) |
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| Bibliography | 1.Wyles JP, McMaster CR, Ridgway ND. Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum. J Biol Chem. 2002 Aug 16;277(33):29908-18. doi: 10.1074/jbc.M201191200. Epub 2002 May 21. PMID: 12023275. |