Primary Information |
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| BoMiProt ID | Bomi10261 |
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| Protein Name | Ubiquitin-conjugating enzyme E2 G2/E2 ubiquitin-conjugating enzyme G2/Ubiquitin-protein ligase G2 |
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| Organism | Bos taurus |
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| Uniprot ID | Q17QG5 |
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| Milk Fraction | Exosomes |
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| Ref Sequence ID | NP_001069796.1 |
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| Aminoacid Length | 165 |
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| Molecular Weight | 18552 |
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| FASTA Sequence |
Download |
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| Gene Name | UBE2G2 |
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| Gene ID | 614471 |
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| Protein Existence Status | Reviewed |
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Secondary Information |
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| Protein Function | The human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) is involved in protein degradation, including a process known as endoplasmic reticulum-associated degradation (ERAD). |
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| Biochemical Properties | UBE2G2 comprises a single domain consisting of an antiparallel β-sheet with four strands (β1–β4), five α-helices (α1–α5) and two 310-helices (η1 and η2).UBE2G2 has the extra long loop (LL) region (95–106), which is probably located on the side near the RING domain. |
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| PTMs | N-acetylation at Ala |
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Site(s) of PTM(s)
N-glycosylation,
O-glycosylation,
Phosphorylation
| na |
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| Predicted Disorder Regions | NA |
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| DisProt Annotation | |
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| TM Helix Prediction | No TM helices |
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| Bibliography | 1.Arai R, Yoshikawa S, Murayama K, Imai Y, Takahashi R, Shirouzu M, Yokoyama S. Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Apr 1;62(Pt 4):330-4. doi: 10.1107/S1744309106009006. Epub 2006 Mar 25. PMID: 16582478; PMCID: PMC2222581. 2. |
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